• Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study 

      Gladstone, Rebecca Ashley; McNally, Alan; Pöntinen, Anna Kaarina; Tonkin-Hill, Gerry; Lees, John A.; Skytén, Kusti Onni; Cléon, Francois Pierre Alexandre; Christensen, Martin Owczarek Korsner; Haldorsen, Bjørg; Bye, Kristina K.; Gammelsrud, Karianne Wiger; Hjetland, Reidar; Kümmel, Angela; Larsen, Hege; Lindemann, Paul Christoffer; Löhr, Iren Høyland; Marvik, Åshild; Nilsen, Einar; Noer, Marie Therese; Simonsen, Gunnar Skov; Steinbakk, Martin; Tofteland, Ståle; Vattøy, Marit; Bentley, Stephen D.; Croucher, Nicholas J.; Parkhill, Julian; Johnsen, Pål Jarle; Samuelsen, Ørjan; Corander, Jukka (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-10)
      Background - The clonal diversity underpinning trends in multidrug resistant Escherichia coli causing bloodstream infections remains uncertain. We aimed to determine the contribution of individual clones to resistance over time, using large-scale genomics-based molecular epidemiology.<p> <p>Methods - This was a longitudinal, E coli population, genomic, cohort study that sampled isolates from ...
    • An Estimate of the Burden of Fungal Disease in Norway 

      Nordøy, Ingvild; Hesstvedt, Liv; Andersen, Cecilie Torp; Mylvaganam, Haima; Kols, Nicola Isabelle; Falch, Birgit Margrethe; Tofteland, Ståle; Müller, Fredrik; Denning, David W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-21)
      The aim of this study was to examine the burden of fungal disease in Norway, contributing to a worldwide effort to improve awareness of the needs for better diagnosis and treatment of such infections. We used national registers and actual data from the Departments of Microbiology from 2015 and estimated the incidence and/or prevalence of superficial, allergic and invasive fungal disease using published ...
    • A Long-Term Low-Frequency Hospital Outbreak of KPC-Producing Klebsiella pneumoniae Involving Intergenus Plasmid Diffusion and a Persisting Environmental Reservoir 

      Tofteland, Ståle; Naseer, Mohammed Umaer; Lislevand, Jan Helge; Sundsfjord, Arnfinn; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Background: To study the molecular characteristics of a long-term, low frequency outbreak of blaKPC-2 in a low prevalence setting involving the hospital environment. Methodology/Principal Findings: KPC-producing bacteria were screened by selective chromogenic agar and Real-Time PCR. The presence of antibiotic resistance genes was ascribed by PCRs and subsequent sequencing, and the KPC-producing isolates ...
    • Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021 

      Ljungquist, Oskar; Haldorsen, Bjørg; Pöntinen, Anna Kaarina; Janice, Jessin; Josefsen, Ellen Haldis; Elstrøm, Petter; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Handal, Nina; Ranheim, Trond Egil; Hansen, Bent-Are; Mjøen, Andreas Fossum; Lindemann, Paul Christoffer; Nilsen, Einar; Zaragkoulias, Kyriakos; Larsen, Hege Elisabeth; Bjørnholt, Jørgen; Gammelsrud, Karianne Wiger; Jakovljev, Aleksandra; Löhr, Iren Høyland; Bredberg, Anders; Marvik, Åshild; Minge, Christina; Tofteland, Ståle; Papp, Kristina; Onken, Annette; Weme, Einar Tollaksen; Guennigsman, Brian Albert (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)
      National and regional carbapenemaseproducing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment recommendations. Aim: This study aimed to describe CPE and their epidemiology in Norway from 2015 to 2021. Methods: A nationwide, population-based observational study of ...